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| Registros recuperados: 51 | |
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| El-Aziz,Tarek Mohamed Abd; Khoury,Sawsan Al; Jaquillard,Lucie; Triquigneaux,Mathilde; Martinez,Guillaume; Bourgoin-Voillard,Sandrine; Sève,Michel; Arnoult,Christophe; Beroud,Rémy; Waard,Michel De. |
| Abstract Background Sperm contains a wealth of cell surface receptors and ion channels that are required for most of its basic functions such as motility and acrosome reaction. Conversely, animal venoms are enriched in bioactive compounds that primarily target those ion channels and cell surface receptors. We hypothesized, therefore, that animal venoms should be rich enough in sperm-modulating compounds for a drug discovery program. Our objective was to demonstrate this fact by using a sperm-based phenotypic screening to identify positive modulators from the venom of Walterinnesia aegyptia. Methods Herein, as proof of concept that venoms contain interesting compounds for sperm physiology, we fractionated Walterinnesia aegyptia snake venom by RP-HPLC and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snake venom; Walterinnesia aegyptia; Bioactive compounds; Fertility; Sperm motility; Venomics; Tandem mass spectrometry; De novo sequencing; Edman degradation. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100301 |
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| Kirinus,Marines Batalha Moreno; Oliveira,Roberto Pedroso de; Silva,Pricila Santos da; Barreto,Caroline Farias; Malgarim,Marcelo Barbosa; Soares Filho,Walter dos Santos. |
| Abstract: The objective of this work was to evaluate the agronomic performance of 'Valência' sweet orange (Citrus sinensis) tree, in combination with 13 rootstocks cultivated in soil and climate conditions of the Brazilian state of Rio Grande do Sul. The following agronomic variables were evaluated: scion height and volume, plant production, production efficiency, productivity, fruit diameter, fruit mass, peel mass, juice yield, soluble solids content, titratable acidity, soluble solids:acidity ratio, ascorbic acid, peel color, antioxidant capacity, and phenolic compounds. A randomized complete block experimental design was used, with three replicates and nine plants per plot, in a two-factor arrangement (13 rootstocks and the 2015 and 2016 harvests). The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citrus sinensis; Bioactive compounds; Fruit quality. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2019000102700 |
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| Manilal,A; Sujith,S; Selvin,J; Shakir,C; Seghal Kiran,G. |
| The antibacterial property of the red algae, Falkenbergia hillebrandii (Born) collected from the southwest coast of India (Indian Ocean) was evaluated against three multidrug resistant human pathogens. Four different solvents: ethyl acetate, dichloromethane, methanol and phosphate buffer saline (PBS) were used with this purpose. Dried samples extracted with methanol showed broadest and highest antimicrobial activity when compared to other solvents. However, PBS extract showed no antibacterial activity. The highly active compounds red alga, F. hillebrandii were fractionated and purified using different chromatographic systems, including reverse phase HPLC and GCMS. The analysis revealed that the most abundant metabolite was the oleic acid (51.33%) followed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; F. hillebrandii; Multidrug resistant human pathogens; Methanolic extract; Bioactive compounds. |
| Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572009000200013 |
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| Ferreira,Maria Jaiana Gomes; Nogueira,Patrícia Coelho do Nascimento; Dias,Flayanna Gouveia Braga; Silva,Larissa Morais Ribeiro da; Silveira,Edilberto Rocha; Figueiredo,Evânia Altina Teixeira de. |
| ABSTRACT: The plant, Amburana cearensis A. C. Smith (Fabaceae), commonly called cumaru, is widespread in the Caatinga cearense, a less known ecosystem in Brazil. A. cearensis is rich in several compounds like protocatechuic acid, tannins, coumarin, flavonoids and phenolic heterosides, such as amburosides A and B, that have been isolated. The aim of this study was to determine the antimicrobial potential and draw the chemical profile of the distinct characteristics of A. cearensis stem bark decoction, for its possible potential as a food conservation agent. The chemical compounds were characterized by one- and two-dimensional 1H and 13C NMR analyses and Liquid Chromatography-Mass Spectrometry (LCMS). The compounds of coumarin, amburosides A and B, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bioactive compounds; Microorganisms; Natural antimicrobials. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000300452 |
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| ALENCAR,DANIEL B. DE; SILVA,SUZETE R. DA; PIRES-CAVALCANTE,KELMA M.S.; LIMA,REBECA L. DE; PEREIRA JÚNIOR,FRANCISCO N.; SOUSA,MÁRCIA B. DE; VIANA,FRANCISCO A.; NAGANO,CELSO S.; NASCIMENTO,KYRIA S. DO; CAVADA,BENILDO S.; SAMPAIO,ALEXANDRE H.; SAKER-SAMPAIO,SILVANA. |
| Natural antioxidants found in marine macroalgae are bioactive compounds known to play an important role in the prevention of diseases associated with aging cells protecting them against the oxidative damage. The purpose of this study was to evaluate the antioxidant and cytotoxic activity of ethanolic extracts of two species of red seaweeds, Amansia multifida and Meristiella echinocarpa. In vitro antioxidant activity was determined by DPPH radical scavenging assay, ferric-reducing antioxidant power (FRAP) assay, ferrous ion chelating (FIC) assay, β-carotene bleaching (BCB) assay and total phenolic content (TPC) quantification. Cytotoxicity was evaluated with the brine shrimp Artemia sp. lethality test. The TPC values observed in the present study indicated... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Bioactive compounds; Cytotoxic; Phenolic compounds; Rhodophyta. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000100251 |
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| Duarte,Patrícia Fonseca; Chaves,Marcia Alves; Borges,Caroline Dellinghausen; Mendonça,Carla Rosane Barboza. |
| ABSTRACT: This study aimed to present a literature review about the characteristics, applications, and potential of avocado (Persea americana). Avocado is considered one of the main tropical fruits, as it contains fat-soluble vitamins which are less common in other fruits, besides high levels of protein, potassium and unsaturated fatty acids. Avocado pulp contains variable oil content, and is widely used in the pharmaceutical and cosmetics industry, and in the production of commercial oils similar to olive oil. This fruit has been recognized for its health benefits, especially due to the compounds present in the lipidic fraction, such as omega fatty acids, phytosterols, tocopherols and squalene. Studies have shown the benefits of avocado associated to a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Avocado tree; Avocado oil; Unsaturated fatty acid; Bioactive compounds. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000400747 |
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| Dias,Flayanna Gouveia Braga; Ferreira,Maria Jaiana Gomes; Silva,Larissa Morais Ribeiro da; Menezes,Rayanne Clécia de Sousa; Figueiredo,Evânia Altina Teixeira de. |
| ABSTRACT Plant diversity around the world, as well as the chemical variation, involves a large amount of bioactive substances. The use of plant extracts with biological properties appears as a viable and healthy alternative when compared to synthetic substances. In this context, the objective of this study was to evaluate the aqueous extracts of native and cultivated leaves of Physalis angulata L., as well as the influence of the extraction method on the bioaccessibility of bioactive compounds, antioxidant activity and antimicrobial activity. The extracts were obtained from the native and cultivated leaves of P. angulata using three different extraction methods: decoction, maceration and an ultrasound-assisted method. The analysis of variance showed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial potential; Antioxidant potential; Bioactive compounds. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902020000300411 |
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| MARINHO-PRADO, J. S.; QUEIROZ, S. C. do N. de; PRADO, S. de S.; ASSIS, M. C. de. |
| Resumo: Os extratos vegetais de quatro espécies das famílias Asteraceae e Verbenaceae foram avaliados quanto a bioatividade sobre as lagartas Anticarsia gemmatalis Hubner, 1818 (Lepidoptera: Erebidae) e Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae). Os extratos hexânicos, diclorometânicos, metanólicos e aquosos de Clerodendrum splendens, Conyza canadensis, Tithonia diversifolia e Vernonanthura westiniana foram oferecidos às lagartas por ingestão em ensaios, avaliando-se a biologia e o comportamento desses insetos. Os extratos vegetais de C. splendens em diclorometano e hexano e de V. westiniana em metanol avaliados sobre A. gemmatalis causaram altas taxas de mortalidade observadas nas lagartas, sendo que o extrato de C. splendens em diclorometano... |
| Tipo: Boletim de Pesquisa e Desenvolvimento (INFOTECA-E) |
Palavras-chave: Vernonanthura westiniana; Clerodendrum splendens; Extrato Vegetal; Praga de Planta; Anticarsia Gemmatalis; Helicoverpa armigera; Bioactive compounds; Conyza canadensis; Tithonia diversifolia. |
| Ano: 2018 |
URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1095015 |
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| Kabiri, Ghizlane; Bouda, Said; Elhansali, Mohammed; Haddioui , Abdelmajid. |
| Biochemical composition and antioxidant activity were determined in kernel nuts for eleven Moroccan walnut (Juglans regia L.) accessions representing its main cropping area. Total oil, carbohydrates, crude protein, energy value, crude fiber and flavonoid have varied significantly between accessions, respectively within the range values of 54.50-65.48%, 8.17-19.25%, 11.5-25.58%, 648.91-713.83 Kcal, 4.17-6.75% and 12.59-62.11mg RE 100 g-1 DM. Besides, mineral composition (mg 100 g-1) of kernel have varied also significantly among accessions and particularly for phosphorus (338.1-675.87), copper (2.08-6.67), zinc (3.39-18.63), iron (1.17-2.64), chromium (0.16-0.20), nickel (1.26-1.45) and boron (0.07-1.49). However, dry matter (96.75-98.56%),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Variation; Proximate composition; Mineral composition; Bioactive compounds. |
| Ano: 2019 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/46411 |
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| Fernandes,Maurette dos Reis Vieira; Silva,Tales Alexandre Costa e; Pfenning,Ludwig Heinrich; Costa-Neto,Cláudio Miguel da; Heinrich,Tassiela Andréa; Alencar,Severino Matias de; Lima,Marisa Aparecida de; Ikegaki,Masaharu. |
| A total of 22 endophytic fungi isolated from coffee (Coffea arabica L.) were cultivated in vitro and their crude extracts tested. The screening was carried out using the agar diffusion method against Staphylococcus aureus, Escherichia coli and Candida albicans. The most effective isolate was Alternaria alternata, and subsequently, its extract was assayed. The total phenolic content was 3.44 μg GAE/mg of the crude extract. For the antibacterial and antifungal activity assays, minimum inhibitory concentrations (MIC) and minimum bactericidal and fungicidal concentrations (MBC and MFC) were determined. The ranges of MIC values were 50-100 μg/mL for S. aureus and 400-800 μg/mL for E. coli. The extract did not show activity in the tested concentrations for C.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Endophytic fungi; Bioactive compounds; Alternaria alternata/extract/antioxidant activity. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400010 |
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| Lima,Fernando Freitas de; Lescano,Caroline Honaiser; Oliveira,Elaine Florinda Rodrigues de; Fakhouri,Farayde Matta; Moraes,Izabel Cristina Freitas; Kassuya,Cândida Aparecida Leite; Sanjinez-Argandoña,Eliana Janet. |
| This study aimed microencapsulating Attalea phalerata Mart. oil, containing high carotenoid and phenolic compounds content, with Arabic gum and gelatin, using the complex coacervation method. The yield, efficiency, morphology of microcapsules and content of phenolic compounds, carotenoids and antioxidant activity in different processes conditions (concentration of the filling, temperature and agitation speed) were evaluated. The results showed 88% of yield, efficiency up to 70% and a characteristic size of microcapsules. The amount of carotenoids was high in crude oil (394.84 µg of carotenoids/g oil) and the microencapsulation tests showed amounts of 19.19 to 166.40 µg of carotenoids/g oil. The phenolic compounds in the crude oil were 20.73 mg GAE/g sample... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Carotenoids; Phenolic compounds; Antioxidant activity; Bioactive compounds; Bioactive maintenance. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100580 |
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| Bruscatto,Mariângela Hoffmann; Zambiazi,Rui Carlos; Crizel-Cardoso,Michele; Piatnicki,Clarisse Maria Sartori; Mendonça,Carla Rosane Barboza; Dutra,Fabiana Lemos Goularte; Coutinho,Enilton Fick. |
| Abstract: The objective of this work was to characterize the chemical composition of olive (Olea europaea) oils produced in Southern of Brazil and correlate it with oxidative stability. Olive oils from the Arbequina, Coratina, Frantoio and Koroneiki cultivars were evaluated. A completely randomized experimental design was used, in a uniform arrangement, with three replicates. Acidity value, peroxide index, specific absorption, tocopherol content, phenolic compound content, carotenoid content, chlorophyll content, fatty acid profile, and oxidative stability were determined. The oils from the Coratina and Frantoio cultivars were classified as extra virgin-oils. The olive oil from the Coratina cultivar showed the highest levels of pigments, followed by the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Olea europaea; Bioactive compounds; Fatty acids; Induction period; Olive; Quality parameters. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2017001201231 |
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| Milivojević,Jasminka; Rakonjac,Vera; Akić,Milica Fotirić; Pristov,Jelena Bogdanović; Maksimović,Vuk. |
| The objective of this work was to evaluate the biochemical composition of six berry types belonging to Fragaria, Rubus, Vaccinium and Ribes genus. Fruit samples were collected in triplicate (50 fruit each) from 18 different species or cultivars of the mentioned genera, during three years (2008 to 2010). Content of individual sugars, organic acids, flavonols, and phenolic acids were determined by high performance liquid chromatography (HPLC) analysis, while total phenolics (TPC) and total antioxidant capacity (TAC), by using spectrophotometry. Principal component analysis (PCA) and hierarchical cluster analysis (CA) were performed to evaluate the differences in fruit biochemical profile. The highest contents of bioactive components were found in Ribes... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bioactive compounds; Metabolite fingerprinting; Multivariate analysis; Nutraceuticals; Small fruits. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2013000900013 |
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| Nogueiras, C.; Spengler, I.; Guerra, J.O.; Ortiz, Y.; Torres, S.; García, T.H.; Romeu, C.R.; Regalado, E.L.; González, T.A.; Perera, W.H.; Lacret, R.. |
| Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in the studies on natural products performed by the “Centro de Estudios de Productos Naturales, CEPN” during the past ten years, highlighting on those with potential use as biomedical... |
| Tipo: Journal Contribution |
Palavras-chave: Products; Chemical compounds; Bioactive compounds; Products; Chemical compounds; Http://aims.fao.org/aos/agrovoc/c_6211; Http://aims.fao.org/aos/agrovoc/c_49870. |
| Ano: 2010 |
URL: http://hdl.handle.net/1834/3986 |
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| Silva,Natalia Kellen Vieira da; Sabino,Luiz Bruno de Sousa; Oliveira,Luciana Siqueira de; Torres,Lucicléia Barros de Vasconcelos; Sousa,Paulo Henrique Machado de. |
| ABSTRACT Guava is a tropical fruit that has a high potential for agroindustrial use, also known antioxidant property mainly attributed to vitamin C and carotenoids content. The objective of this study was to evaluate the influence of food preservatives, individually or combined, on the antioxidant properties of red guava nectar during storage. Nectars added of different additives were stored in the dark for 180 days and evaluated at the processing day and every 90 days for physico-chemical parameters, color, bioactive compounds content, total antioxidant activity (TAA), the microbiologica and sensory quality. Was not observed changes in quality parameters (P>0.05), since the guava nectars were presented in accordance with Standards of Identity and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Psidium guajava; Chemical additives; Bioactive compounds; Stability. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902016000100077 |
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| Nascimento-Costa,Laíse; Souza-Freitas,Wallace Edelky de; Morais,Patrícia Lígia Dantas-de; Morais,Divanóvina Laís-de; Mendonça,Vander. |
| Abstract This study aimed to evaluate the effect of nitrogen fertilization on the physical and physico-chemical characteristics and antioxidant potential of sapodilla at different stages of development. The experiment was installed at the Norfruit farm, located in the rural community of Pau Branco, Mossoró/RN, Brazil. A randomized block with two factorial schemes experimental design, was adopted. The first 5 x 6 with lost parcels, consisting of five doses of nitrogen (N) (0, 300, 600, 900 and 1200 g of N.plant-1) and six stages of fruit development; and the second 2 x 3 consisting of two levels of nitrogen (N) (0; 600 g of N plant-1) and three stages of development, both with five replications. The fruits were labeled with a 10 to 15 mm long mark in the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bioactive compounds; Chemical composition of fruits; Mineral nutrition; Ripening. |
| Ano: 2017 |
URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-28122017000400480 |
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| Registros recuperados: 51 | |
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